Andrographis paniculata (King of Bitters): A Phytogenic Powerhouse for Animal Health

1. Introduction

Andrographis paniculata commonly known as “King of Bitters,” is a medicinal herb recognized for its potent antimicrobial, immunomodulatory, and hepatoprotective properties. Traditionally used in Ayurveda and Traditional Chinese Medicine, this herb has gained significant interest in modern veterinary science for its ability to enhance animal health and performance. Its applications in poultry, swine, ruminants, aquatic species, and companion animals are driven by its bioactive compounds, which exhibit strong anti-inflammatory and immune-boosting properties.

2. Organoleptic Properties

• Color: Green to brownish-green powder
  
• Odor: Characteristic bitter herbal aroma
  
• Taste: Intensely bitter
  
• Solubility: Partially soluble in water; highly soluble in alcohol-based solutions
  
• Particle Size: Available in various mesh sizes tailored for different feed and supplement applications
  

3. Key Bioactive Compounds

Andrographis paniculata is rich in several bioactive constituents, including:

• Andrographolide – Primary active compound known for its anti-inflammatory and immunomodulatory effects.
  
• Neoandrographolide – Supports liver health and metabolic functions.
  
• Deoxyandrographolide – Exhibits antimicrobial and antioxidant properties.
  
• Andrographiside – Enhances gut health and overall digestion.

4. Purpose and Usage by Species

Poultry

• Improves Gut Health and Reduces Pathogenic Bacterial Load: Supplementation with Andrographis paniculata has been shown to decrease gut coliform levels and enhance the performance of Tegal ducks. [1]
  
• Enhances Immune Response Against Viral Infections: The herb’s immunostimulant properties have been documented in traditional medicine, suggesting potential benefits in poultry immune responses. [2]
  
• Supports Liver Function and Detoxification: Andrographis paniculata possesses hepatoprotective properties, aiding in liver health and detoxification processes in poultry. [3]
  

Swine

• Reduces Incidence of Post-Weaning Diarrhea: The antimicrobial properties of Andrographis paniculata can help mitigate bacterial infections, potentially reducing diarrhea in piglets. [4]
  
• Supports Immune Modulation in Weaned Piglets: The herb’s immunomodulatory effects may enhance the immune system of weaned piglets, promoting better health and growth. [5]
  
• Improves Feed Efficiency and Weight Gain: Supplementation with Andrographis paniculata has been associated with improved growth performance and feed conversion ratios in livestock. [6]
  

Ruminants

• Enhances Rumen Fermentation and Nutrient Digestibility: The addition of phytogenic feed additives containing Andrographis paniculata has been shown to improve nutrient digestibility in ruminants. [7]
  
• Supports Liver and Metabolic Health in High-Yielding Dairy Cows: The hepatoprotective properties of Andrographis paniculata can aid in maintaining liver health in dairy cows under metabolic stress. [8]
  
• Acts as a Natural Anti-Inflammatory Agent for Joint Health: The anti-inflammatory properties of the herb may help in managing joint inflammation in ruminants. [9]
  

Aquatic Animals

• Improves Survival Rate in Shrimp and Fish Under Pathogen Challenge: Dietary supplementation with andrographolide has been shown to enhance growth performance and immune responses in aquatic species. [10]
  
• Enhances Antioxidant Capacity and Stress Resilience: Andrographis paniculata supplementation has been linked to improved antioxidant status and stress resilience in aquatic animals. [11]
  
• Supports Intestinal Microbiota Balance in Aquaculture: The herb’s antimicrobial properties can help maintain a healthy gut microbiota in aquaculture species. [12]
  

Companion Animals (Dogs & Cats)

• Boosts Immune Function in Aging Pets: Andrographis paniculata’s immunomodulatory properties may enhance immune responses in aging dogs and cats. [13]
  
• Supports Liver Detoxification and Overall Vitality: The hepatoprotective effects of the herb can aid in liver health and overall vitality in companion animals. [14]
  
• Aids in Managing Inflammatory Conditions Such as Arthritis: The anti-inflammatory properties of Andrographis paniculata may help alleviate symptoms of arthritis in pets. [15]
  

5. Standardized Botanical Powders Offering

Our Andrographis paniculata offerings include:

• Crude Powder – Ideal for bulk feed formulations
  
• Standardized Extract (10%-50% Andrographolide) – For precision supplementation
  
• Granular Form – Enhanced for improved palatability and mixing in feed applications

6. Synergistic Phytogenic Combinations

Andrographis paniculata works effectively in combination with other phytogenic ingredients, including:

• Turmeric (Curcuma longa) – Enhances anti-inflammatory and antioxidant effects.
  
• Garlic (Allium sativum) – Synergistic antimicrobial properties for gut health.
  
• Neem (Azadirachta indica) – Provides additional immune-boosting and antiparasitic benefits.
  

References

1. researcherslinks.com
2. PubMed Central
3. PubMed Central
4. cxbt-showvet.en.made-in-china.com
5. cxbt-showvet.en.made-in-china.com
6. PubMed Central
7. bmcvetres.biomedcentral.com
8. PubMed Central
9. PubMed Central
10. mdpi.com
11. mdpi.com
12. mdpi.com
13. cxbt-showvet.en.made-in-china.com
14. cxbt-showvet.en.made-in-china.com
15. cxbt-showvet.en.made-in-china.com

FDA Disclaimer

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult a veterinarian before using this supplement in animal feed formulations.